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Nicotine & Tobacco Research Advance Access originally published online on July 24, 2009
Nicotine & Tobacco Research 2009 11(10):1231-1244; doi:10.1093/ntr/ntp112
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© The Author 2009. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oxfordjournals.org

Transdisciplinary Tobacco Use Research Centers: Research achievements and future implications

Timothy B. Baker, K. Michael Cummings, Dorothy K. Hatsukami, C. Anderson Johnson, Caryn Lerman, Raymond Niaura and Stephanie S. O’Malley

Timothy B. Baker, Ph.D., Center for Tobacco Research and Intervention, University of Wisconsin School of Medicine and Public Health, Madison, WI
K. Michael Cummings, Ph.D., MPH, Department of Health Behavior, Roswell Park Cancer Institute, Buffalo, NY
Dorothy K. Hatsukami, Ph.D., Department of Psychiatry, University of Minnesota, Minneapolis, MN
C. Anderson Johnson, Ph.D., School of Community and Global Health, Claremont Graduate University and Claremont University Consortium, San Dimas, CA
Caryn Lerman, Ph.D., Department of Psychiatry, University of Pennsylvania, Philadelphia, PA
Raymond Niaura, Ph. D., Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI
Stephanie S. O’Malley, Ph.D., Department of Psychiatry, Division of Substance Abuse, Yale University School of Medicine, New Haven, CT

Corresponding Author: Timothy B. Baker, Ph.D., Center for Tobacco and Intervention, Department of Medicine, 1930 Monroe Street, Suite 200, Madison, WI 53711. Telephone: 608-262-8673; Fax: 608-265-3102; E-mail: tbb@ctri.medicine.wisc.edu

Received: September 25, 2008; Accepted: December 31, 2008
The first 150 words of the full text of this article appear below.


   University of Wisconsin
 
Focus of the center
The University of Wisconsin Transdisciplinary Tobacco Use Research Center (TTURC) has focused on several linked topics: (a) improving our assessment and understanding of nicotine dependence, (b) exploring factors that cause or modulate relapse risk, (c) identifying genetic influences on nicotine dependence and cessation success, and (d) testing smoking cessation interventions and determining their mechanisms of action.

Key findings
Development of a new multifactorial instrument to assess nicotine dependence.
This developmental research effort produced a new questionnaire that is now being widely used to assess nicotine dependence: the Wisconsin Inventory of Smoking Dependence Motives (WISDM-68), which has good psychometric properties and is appropriate for use with a broad range of smokers (men and women, ethnic minorities; Piper et al., 2004). This work also produced direct evidence that nicotine dependence is indeed multidimensional, revealing which aspects of dependence are most associated with heightened relapse risk, withdrawal severity, and heavy smoking (Piper et al.).

Insight into the nature of nicotine dependence.
Research with the WISDM-68 suggests that four core features of . . . [Full Text of this Article]

Insight into mechanisms via which nicotine dependence leads to relapse back to smoking.
The genetics of nicotine dependence.
Characterizing smoking treatment effectiveness.
How cessation treatments work.
Implications
Future plans

   Roswell Park Cancer Institute
 
Focus of the center
Key findings
Future plans

   University of Minnesota
 
Focus of the center
Key findings
Implications

   University of Southern California/Claremont Graduate University
 
Focus of the center
Key findings
Socially and genetically acquired influences on smoking and alcohol abuse.
Prevention relative to cultural composition of the community.
Dispositional characteristics of the individual.
Cultural environment by disposition by program interactions (E x P x E).
Genes, abuse trajectories, and prevention.
Emotional decision capacity and tobacco–alcohol abuse trajectories.
Implications
Future research
Societal impact

   University of Pennsylvania
 
Focus of the center
Key findings
Summary

   Brown University
 
Focus of the center
Key findings and implications

   Yale University
 
Focus of the center
Key findings
Depression.
Alcohol use.
Female gender.
Future directions

   Funding
 

   Declaration of Interests
 

   Note
 

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